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Mississippi roast Instant Pot served with gravy and pepperoncini on a white plate

Instant Pot Mississippi Roast

Fork-tender beef cooked in the Instant Pot with ranch, au jus, and pepperoncini for a bold, comforting roast that’s perfect for busy weeknights or Sunday dinners.
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Course: dinner, Main Course
Cuisine: American, Southern
Keyword: Mississippi pot roast crock pot, Mississippi pot roast Instant Pot 4 ingredients, Mississippi Pot roast Instant Pot no packets, Mississippi pot roast recipe, Mississippi roast instant pot time
Prep Time: 10 minutes
Cook Time: 1 hour 10 minutes
Natural Pressure Release: 15 minutes
Total Time: 1 hour 35 minutes
Servings: 6
Calories: 420kcal
Cost: $18

Equipment

  • 1 Instant Pot (6 or 8 quart)
  • 1 Tongs or meat claws
  • 1 Small Bowls
  • 1 Forks

Ingredients

  • 3–4 lb Chuck roast Well-marbled preferred
  • 1 Ranch seasoning packet (1 oz) or homemade
  • 1 Au jus gravy packet (1 oz) or beef bouillon
  • ½ cup Pepperoncini peppers Whole or sliced
  • ¼ cup Pepperoncini juice From the jar
  • 1 stick Butter (8 tbsp), cut into chunks

Instructions

  • Pat the roast dry and season with salt and pepper
  • Sear in the Instant Pot using sauté mode (optional)
  • Sprinkle ranch and au jus seasoning into pot
  • Add roast back in, layer pepperoncini, juice, and butter on top
  • Pressure cook on high for 60–75 minutes (based on size)
  • Natural release for 15 minutes, then quick release
  • Shred meat and return to pot with some liquid
  • Optional: sauté 5–10 mins after shredding for crispy edges

Notes

Nutrition information is automatically calculated, so should only be used as an approximation.

Nutrition

Serving: 200g | Calories: 420kcal | Carbohydrates: 2g | Protein: 35g | Fat: 30g | Saturated Fat: 14g | Polyunsaturated Fat: 2g | Monounsaturated Fat: 12g | Trans Fat: 1g | Cholesterol: 130mg | Sodium: 860mg | Potassium: 610mg | Sugar: 1g | Vitamin A: 480IU | Vitamin C: 3mg | Calcium: 30mg | Iron: 3.1mg